On February 11, 2021, a research article entitled "Mediator structure and conformation change" was published in Molecular Cell. This report, based on a joint effort of the Lab of Structure Biochemistry at Shanghai Institute for Advanced Immunochemical Studies (SIAIS) and collaborators from Stanford describes, for the first time, the cryo-EM structure of the entire Mediator at a near...

As one of the most popular fields in artificial intelligence, deep neural network (DNN) is a promising approach to realize many AI tasks such as speech recognition, image classification and autonomous driving. At the same time, with advances in the technology of edge computing and internet of things, it is necessary to deploy pretrained DNN models at the edge of networks and on the terminal device...

Electromagnetic imaging technology with array sensors is used extensively to detect defects in industries where structural integrity and safety are critical, such as aerospace, high-speed railway, pressure vessels, energy facilities and precision manufacturing. SIST Assistant Professor Ye Chaofeng and his research group in the Precision Sensing and Intelligent Testing lab (PSIT) have designed two ...

Genomic imprinting is essential for mammalian embryonic development, and is an epigenetic phenomenon present in higher animals and plants. Dysregulation of the imprinted genes causes diabetes, cancer and neurological disorders. Understanding the expression regulation mechanism of imprinted genes can help us understand human individual development and disease etiology and treatment.  In a...

Recent studies have associated the aberrant accumulation of adipocytes in the heart  with many cardiovascular diseases such as arrhythmogenic right ventricular cardiomyopathy and heart failure. Therefore, understanding the cellular origins of cardiac adipocytes (CAs) has important implications for the treatment of fat-associated cardiovascular diseases. Recently, a team of scientist...

On December 1st, 2020, Professor Tiffany Horng from the SLST published an invited review article entitled “Lipid Metabolism in Regulation of Macrophage Functions” in the journal Trends in Cell Biology. In this review, Professor Horng and her postdoc Dr. Yan Jiawei describe the processes whereby signals that regulate macrophage activation influence lipid metabolic pathways and modulate macro...

Data storage is one of the fundamental systems in computer architecture. There are a variety of data structures to implement data indexing at a high speed in a computer system. B+-Tree, a data structure designed for disks and single-core processors proposed in the 1970s, is currently still indispensable in many databases and file systems. One of the promising data storage devices to transplant and...

 Recently, the winners of the 45th International Collegiate Programming Contest (ICPC) Asian Regional Competition (Nanjing Station) were announced. The ShanghaiTech University representative team, composed of three undergraduate students from the SIST, won the gold award. This was the first time that ShanghaiTech has won the gold award in the computer algorithm competition.  ICPC is...

On January 15, 2021, Professor Luo Zhenge and his colleagues at the School of Life Science and Technology (SLST) published a paper entitled, “TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a”, in the journal Science Advances. The cerebral cortex of mammals controls sensory input, motor output, learning and memory, deci...

 On January 8, 2021, Mr. Vincent Hieff, Consul General of Luxembourg in Shanghai, and Ms. Ma Ying, Senior officer Financial Sector, visited ShanghaiTech University. Jiang Ge, Vice President and Executive Director of SIAIS, welcomed them together with representatives from the Office of International Affairs. Jiang Ge extended a warm welcome to Mr. Hieff and Ms. Ma, and introduced the hist...

The Center for Intelligent Power and Energy Systems (CiPES) of SIST is a subdivided research group focusing mainly on the study of electric power and energy. It studies topics including power generation, transmission/distribution, storage and utilization, and aims to propose reliable, efficient, low-carbon and intelligent power solutions for the sustainable development of domestic energy. Recently...

Ambient energy harvesting technology provides the most promising energy solution for future battery-less, ubiquitous, and maintenance-free Internet of Things (IoT) devices. Among all types of ambient energy sources, mechanical kinetic energy can be better associated with human and machine movements, as there is plenty of motion information combined with the mechanical movements of parts. The resea...

Recently, the news report entitled The two core conjectures of differential geometry were finally proved after more than 20 years was selected as one of the top ten domestic science and technology news reports of 2020.This report about mathematics research describes the convergence of high-dimensional Kellerridge flow, and was published by the IMS Founding Director Chen Xiuxiong and Professor...

The SEM course entitled Design Thinking: Scheme Design in Entrepreneurship and Management held its closing roadshows for the fall semester of the 2020-2021 academic year in the SEM lecture hall on December 21st and 24th. For this semester the course was organized by eight professors from the SEM, and two classes were run. Prof. Hong Suting, the host of the roadshow, gave a brief introduction ...