报告人简介： 金晨羽，现为欧盟“玛丽·居里学者”，在卢森堡大学从事活性物质与微生物生物物理方向的研究。 教育与研究背景跨越多个学科和领域，在上海交通大学获得了生物技术学士和化学硕士，在德国马克斯－普朗克胶体与界面研究所取得物理化学博士学位，随后在马克斯－普朗克动力学与自组织研究所、德国拜罗伊特大学、卢森堡大学从事博士后研究。 研究聚焦于活性软物质在复杂环境中的感知、响应及适应机制，旨在揭示其背后的普适...

The eukaryotic genome is tightly compacted in the nucleus as chromatin, with the nucleosome core particle (NCP) as its basic unit, comprising of ~145 base pairs of DNA wrapped around a histone octamer (two copies each of H2A-H2B and H3-H4). Despite this dense packaging, regulatory processes like transcription, replication, and repair must access DNA, necessitating chromatin remodeling. While chrom...

在全球科技竞争日趋激烈的背景下，新一代通信技术已成为大国博弈的核心战场。当前，5G-A技术加速向“万物智联”演进，6G通感融合网络更以其“空天地海”全域覆盖能力，引领通信架构的革命性升级。 4月18日，2025年第二期（总第23期）ShanghaiTech Lecture邀请中国科学院声学所研究员、原中国科学院秘书长、原中国科学院声学所所长侯自强继续带来“星辰大海”系列第三讲，从5G-A技术演进，到6G网络的关键技术、战略布局与产业赋能，...

The committor functions are central to investigating rare but important events in molecular simulations. It is known that computing the committor function suffers from the curse of dimensionality. Recently, using neural networks to estimate the committor function has gained attention due to its potential for high-dimensional problems. Training neural networks to approximate the committor function ...

The TGF-β superfamily plays crucial roles in normal development and physiology. Precise control of TGF-β signaling strength and duration is essential, and dysregulation of this pathway is implicated in the pathogenesis of various human diseases, notably cancer. A hallmark of many cancers is the loss of the TGF-β antiproliferative response, allowing tumor cells to escape growth control. A key me...