Memory is stored in neural networks via changes in synaptic strength mediated by long-term potentiation (LTP). Here we show that a cholecystokinin (CCK)-B-receptor antagonist blocks high-frequency stimulation (HFS)-induced neocortical LTP, whereas local infusion of CCK induces LTP in the auditory cortex. We identified that entorhinocortical terminals release CCK, which enables neocortical LTP and ...

Relativistic interactions with matter involving heavy high-Z ions provide a unique testing ground for our understanding of quantum electrodynamics and correlation in the non-perturbative regime as well as of elementary atomic processes mediated by ultrafast electromagnetic interactions. For this realm of physics, the future international accelerator Facility for Antiproton and Ion Research (FAIR) ...

展览简介:本次图文展精选上海博物馆馆藏文物中20件最具创造性的器物，从技术、工艺设计和匠人精神等方面阐述古代造物智慧，并加入展现当代上博人文物修复技艺和理念的故事案例，古今结合，呈现文化传承中的智慧之光。 文物修复工作坊活动简介:上海博物馆副研究馆员、上海市非物质文化遗产传承青年人才、国家级非物质文化遗产代表项日“古陶瓷修复技艺”第五代传人张力程将带领学员一同体验破损瓷瓶的修复。瓷瓶的修复将通过清洗、...

The shift from hypothesis-driven biomedical research to data-driven, AI-led approaches is a hallmark of the current era of rapid advances in AI technologies and growing availability of multi-omics data that characterize cellular states at various molecular levels. Similar to how natural languages describe the physical world, genes can be seen as the "words" of life's genetic language. In...