The biomedical field has embraced the medical digital twin (DT) as a transformative goal, aimed at modeling individual patient health, forecasting disease trajectories, and guiding personalized interventions in real time. While the creation of a multi-organ, d multi-omics MDT remains Dr. Wen's long-term aspiration and is still in its very early stages, Dr. Wen's current research focuses on develop...

The "Valley of Death" remains a formidable barrier in biomedicine, where countless promising scientific discoveries fail to translate into viable therapeutics. This seminar will address the critical challenges that cause this attrition, spanning the entire value chain from initial target validation and compound generation to preclinical and clinical assessments of safety and efficacy. W...

9月27日，秋意渐浓，“秋野”呼应时节的开阔感，“星栖”以星辰暂落原野为喻，寓意大一、研一新生如散落在校园的星光，带着各自的光芒汇聚于此，既有静谧的诗意，又暗含“相聚”的温暖。“潮起”与“星栖”形成动静对照，以浪潮奔涌的动态感，象征新生们怀揣热忱开启大学新旅程，充满向前的力量；“新澜”直指“迎新”核心，呼应他们即将书写的新篇章。 9月27日18:30，上海科技大学2025新生晚会将于会议中心正式启幕，邀请所有老师...

Given their increasing ubiquity it is of the utmost importance to ensure that AI systems can represent a diverse set of human values and perspectives. Meanwhile progress on this type of control of Large Language Models (LLMs) has been hampered by a fundamental underlying problem in generative models: the difficulty of evaluating their behavior. With their enormous range of inputs and responses an...

Adaptive deep brain stimulation (aDBS) for Parkinson’s disease recently joined responsive neurostimulation (RNS) for epilepsy as an approved closed-loop brain stimulation therapy in the United States. In addition to improving quality of life for patients, these bi-directional brain-computer interfaces (BCIs) are invaluable tools for improving our understanding of brain circuits and eventually tra...