Trifluoromethylation for PET applications
The continued expansion of positron emission tomography (PET) imaging hinges on the development of efficient radiolabeling strategies that can rapidly incorporate short-lived radionuclides into complex molecules. However, the installation of radiolabeled trifluoromethyl (CF₃) groups at unactivated C(sp³) centers remains a long-standing challenge, limiting access to a broad class of bioactive trace...
2026-04-30