A team of scientists led by Professors Liu Zhi-Jie and Hua Tian at the iHuman Institute of ShanghaiTech University has determined and analyzed the high-resolution atomic structures of human cannabinoid receptors, also known as the “marijuana receptors”, 1 and 2 (CB1 and CB2) complexed with their agonists and downstream signaling G proteins. The results, described in a paper entitl...

Recently, the paper acceptance results of the 19th International Joint Conference on Autonomous Agents and Multi-Agent Systems (AAMAS-2020) and the 24th European Conference on Artificial Intelligence (ECAI-2020) have been announced. Five papers from Professor Zhao Dengji's research group of SIST were accepted. It is worth mentioning that the first authors of the accepted papers are n...

From January 8th to 9th, an International Assessment Committee conducted a comprehensive review of the School of Entrepreneurship and Management (SEM)’s first five years since its launch. The committee consisted of five internationally distinguished experts, chaired by Professor Richard Lyons (Chief Innovation & Entrepreneurship Officer and Former Dean of the Haas School of Business, UC Berke...

Research teams led by SPST Assistant Professor Ji Quanjiang and Fudan University Professor Gan Jianhua recently used structural biology, biochemical, and cell-based genome editing experiments to reveal the mechanisms of the PAM expansion and fidelity enhancement of a new evolved Cas9 nuclease xCas9. Their work, “Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuc...

iHuman Institute and SLST Professor Shui Wenqing’s group published a review in Current Opinion in Biotechnology in October 2019, “Systematic mapping of protein-metabolite interactions with mass spectrometry-based techniques”. This review presents a comprehensive overview of chemical proteomics techniques developed for probing protein-metabolite interactions in the cell. Shui Wenqing’...

A research group led by iHuman Institute and SLST Assistant Professor Zhao Suwen, working with Professor Wang Ming-Wei from Shanghai Institute of Materia Medica/The National Center for Drug Screening/Fudan University and Professor Babu Madan from MRC Laboratory of Molecular Biology, recently discovered a common activation pathway in class A GPCRs. Their study, “Common activation mechanism of clas...

Liquid sorbents, such as water, polyethylene glycol (PEG), and organic amine solutions, are widely used in many industrial processes for acid gases removal. This process is called wet scrubbing. However, most liquid sorbents have high vapor pressure and are sometimes even corrosive to the equipment. These undesirable features greatly increase the cost of separation and complicate facility design. ...

Recently, a research group led by SPST’s Dr. Ji Quanjiang established an efficient genome engineering platform in Acinetobacter baumannii firstly. Their research was published in Cell Chemical Biology with the title of “A highly efficient CRISPR-Cas9-based genome engineering platform in Acinetobacter baumannii to understand the H2O2-sensing mechanism of OxyR”.This platform allows...

Halide perovskite shows great potential as the most promising next generation of high-efficiency and low-cost solar cells. Currently, the main problem for the perovskite solar cell is the incompatibility of high stability and high efficiency. For example, the stability of inverted structure perovskite solar cells is good, but the efficiency is low, especially for the NiOx-based inverted structure ...

The competition and interaction of different entangled degrees of freedom can generate many interesting phenomena, one of the most active research topics in contemporary condensed matter physics. Recently, the research groups of Assistant Professors Li Gang, Liu Zhongkai, and Guo Yanfeng studied the low-dimensional ferromagnetic system CrSiTe3 and successfully revealed the important role play...

Recently, ACS Nano published an article jointly contributed by research teams led by SPST Professors Xue Jiamin and Professor Guo Yanfeng and Shanghai Institute of Technical Physics Professor Hu Weida. Their work, “Nb2SiTe4: A Stable Narrow-Gap Two-Dimensional Material with Ambipolar Transport and Mid-Infrared Response,” reported an important research advance in new narrow-bandgap two-dimen...

Dr. Yang Haitao, Shanghai Institute of Advanced Immunochemical Institute (SIAIS) Principal Investigator, recently was awarded the 2019 Youth Shu Lan Medicine Award, marking the first time a ShanghaiTech faculty member won this  prize.Youth Shu Lan Medicine Award Winners and the PresentersThe Shu Lan Medicine Awards, first awarded in 2014, recognize distinguished scientists and scholars. Youth...

When that newest issue of Cell arrives, or you're checking out the latest articles in Nature, have you ever stopped to think about where the cover images and accompanying illustration come from? With their support, ShanghaiTech scientists’ groundbreaking research can jump from the page in full color and excite the reader.  Julie Liu, an illustrator who joined ShanghaiTech as a ...

DREAM 2019 Challenge organizers recently announced competition and the ShanghaiTech team from SIST named “SingleCellLand” won the Third Place (out of 291 teams worldwide) in the first sub-challenge. The team was guided by Professor Zheng Jie, the director of SIST’s Smart Medical Information Research Center (SMIRC). Other team members include Professor Zheng’s master’s degree students Dai Xinn...