ShanghaiTech University

Joule

New Principle for Efficient CO₂ Mitigation Discovered

A team of researchers led by Professor Lin Bolin at ShanghaiTech University have discovered a new principle for efficient CO2 mitigation, and, for the first time, explicitly overturned the dominant paradigm that the use of fossil fuel power to drive CO2 chemical reductions would create more CO2 emissions than it would reduce CO2. The researchers propose a progressive strategy for gl...

2018-03-05
Nature Microbiology

New Progress on Zika Virus Elucidites Role of AXL in Promoting ZIKV Infection

Nature Microbiology recently made available as an Advance Online Publication the research findings of a collaboration between SIAIS Research Associate Professor Liu Jia from the Laboratory of ADC Chemistry and Professor Xu Jianqin from Fudan University Shanghai Public Health Clinical Center on new progress on Zika virus, elucidating the role of AXL in promoting Zika virus (ZIKV) infection.ZIK...

2018-02-26
Cell

Next Steps Towards Deciphering a New Paradigm in Drug Discovery

Polypharmacology is the next generation of disease treatment, promising more effective drugs that are less toxic and have fewer side effects. However, polypharmacological drugs, which simultaneously act on multiple targets, remain extremely difficult to develop, though maybe not for long, according to a study published this week in Cell.Apparently, the key lies in obtaining a better understanding ...

2018-02-02
Advanced Materials

In Situ Real-Time Study Sheds Light on Perovskite Films

The direct conversion of solar energy to electrical power is widely regarded as a key technology to tackle the energy crisis in a sustainable manner. Among innovative technologies, metal halide perovskite solar cells (PSCs) have advanced to the forefront of solution-processed photovoltaic techniques, promising for high power conversion efficiency and low cost. Currently, the technique involving th...

2018-01-29
Nature Neuroscience

Study Advances Complex Gene Network Brain Research in Mammals

Nature Neuroscience recently published a study demonstrating that the transcription of multiple genes in the brain can be simultaneously activated using CRISPR–dCas9-activator transgenic mice. This work was performed by researchers in Dr. YANG Hui’s lab at the Institute of Neuroscience and State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Techn...

2018-01-26
Advanced Materials

Researchers Develop Highly Efficient Inverted Structural Quantum Dot Solar Cells

Under the support of the National Key Research and Development Program titled “High stability, full spectrum, high-efficiency solar cells materials exploration and device realization,” the School of Physical Science Technology’s Ning Zhijun Group explored Lead Sulfide (PbS) as the active layer and developed highly efficient inverted structural quantum dot (QDs) solar cells. Recently, their work...

2018-01-23
Physical Review Letters

Spin-Based NDR Effect Experiment Advances Atomic-Scale Magnetic Sensor Research

A collaborative research project between Yan Shichao, an assistant Professor in School of Physical Science and Technology at ShanghaiTech University and Professor Sebastian Loth at Max Planck Institute in Germany discovered the spin-based NDR effect in antiferromagnetically coupled few-atom spin chains. Their research paper on the “Dynamical Negative Differential Resistance in Antiferromagne...

2017-12-19
Nature Structural and Molecular Biology

APOBEC's Effect on Gene Editing Revealed

A team of scientists led by Dr. Jia Chen in the School of Life Science and Technology at ShanghaiTech University, Dr. Li Yang in the CAS-MPG Partner Institute for Computational Biology at the Chinese Academy of Sciences, and Dr. Bin Shen in the State Key Laboratory of Reproductive Medicine in the Department of Histology and Embryology at Nanjing Medical University has revealed that APOBEC3 induces...

2017-12-13
ACS Editors' Choice

Major Breakthrough in CO₂/Olefins-Based Polymeric Materials Synthesis

Recently, School of Physical Science and Technology (SPST) Assistant Professor Lin Bolin’s research group made a major breakthrough in CO2/olefins-based polymeric materials synthesis and was selected in ACS Editors’ Choice. Combining green-house gas CO2 with a low cost olefin, they provided a convenient and highly efficient methodology for synthesis of functionalizable polymeric materials. ...

2017-10-03
Journal of American Chemical Society

Mesoporous MOFs Achieve New Record in Ultrahigh Capacity Methane Storage

Zhang Yuebiao's group in the School of Physical Science and Technology at ShanghaiTech University developed a new series of mesoporous metal organic frameworks (MOFs) and achieved a new record in ultrahigh capacity methane storage. These results have been published in the Journal of the American Chemical Society with the title of “Engineering of Pore Geometry for Ultrahigh Capacity ...

2017-09-15
Angewandte Chemie International Edition

Acid-Labile Molecular Container for Controlled Drug Release Developed

In a recent study, Research Associate Professor Liu Jia from SIAIS and Professor Ma Da from Fudan University developed an acid-labile acyclic cucurbit[n]uril (CB[n]) molecular containers for controlled drug release. Their study was published on Angewandte Chemie International Edition.Pathological conditions such as tumors often lead to acidic microenvironment, making acid-labile drug carriers attr...

2017-09-12
Hepatology

Liver Regeneration Findings Highlight Important Role of IGF-2

A team led by Assistant Professor Huang Pengyu at ShanghaiTech University’s School of Life Science and Technology, collaborating with Sun Yat-sen Memorial Hospital at Guangzhou, found an important role of IGF-2 in liver regeneration induced by some chronic liver injuries. Their work entitled “Pericentral hepatocytes produce IGF-2 to promote liver regeneration during special injuries” was publis...

2017-09-07
Cell Research

Enhanced Base Editing by Co-expression of Free Uracil DNA Glycosylase Inhibitor

Genome editing is a type of genetic engineering, which utilizes programmable nucleases such as the Cas9 nuclease to achieve desired base insertion, deletion or substitutions in the genome of living organisms. Directed by guide RNA (gRNA), Cas9 nuclease can generate DNA double strand breaks (DSBs) at targeted genomic sites. Subsequent resolving of the generated DSB through non-homologous end joinin...

2017-08-31
Science

Mysterious Majorana Particle Identified

In our universe, everything is made up of elementary particles. Some – like photons - are already well-known; others remain to be unveiled. Recently, a group of engineers and scientists has found the “smoking gun” signature of the long sought-after Majorana particle. This research, led by Professor Kang L. Wang at UCLA (also an adjunct professor at SIST), was published in Science on July 21...

2017-08-09

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