On December 20, GT919, the first molecular glue pipeline for oral administration of Gluetacs Therapeutics, a ShanghaiTech-incubated pharmaceutical company, obtained the implied permission for clinical trials from the Center for Drug Evaluation (CDE). Founded in 2020, Gluetacs has raised venture capital of more than 100 million yuan, and signed exclusive patent licensing agreements with ShanghaiTec...

The 15th C.C. Tan Life Science Awards Ceremony was held at ShanghaiTech University on December 10. A total of 17 scientists won C.C. Tan Life Science Awards this year. The ceremony was presided over by CAS Academician Rao Zihe, who also serves as the Chair of the Award Committee and a Distinguished Adjunct Professor of ShanghaiTech. The celebration was held both virtually and on-site. CAS Aca...

On November 20, a grand 10-year Anniversary Celebration event for iHuman Institute was held at the Conference Center. The celebration, which is also the first iHuman Alumni Symposia, was hosted by Liu Zhi-Jie, Dean of the Dadao College and Executive Director of iHuman Institute. Liu Zhi-Jie hosted the celebration eventA 10-minute celebration video clip was played at the beginning, showing the...

On December 2, the first International Session of ShanghaiTech Innovation and Entrepreneurship Summit (techIES) was held as a hybrid event, with both in-person and live stream options. Deputy Director of International Affairs Dr. Nie Yan delivered the opening speech and Assistant Director Ms. Xiao Yin hosted the event. The International Session has attracted 13 projects from six countries. Eventua...

First Prize: “DOVE”Second Prize: “Rediscovering in silico MHC-I peptide misses as new starting points for future therapeutics”Third Prize: “Identifying promising non-coding silencers as druggable hits and targeting the dark side of the genome”

In the 2022 IEEE Asia Pacific Conference on Circuits and Systems (IEEE APCCAS) held in Shenzhen from November 11 to 13, a paper co-authored by ShanghaiTech graduate students won the Best Paper Award. The paper is entitled “Hierarchical and Recursive Floorplanning Algorithm for NoC-Based Scalable Multi-Die FPGAs”, whose co-authors are second-year master student Luo Jianwen, fifth-year Ph.D. ...

Recently, a group led by Distinguished Adjunct Professor Roger Kornberg and Research Associate Professor Zhang Heqiao of the laboratory of structure biochemistry at SIAIS, published a paper entitled “Structure of the NuA4 histone acetyltransferase complex” in the Proceedings of the National Academy of the Sciences (PNAS), reporting a near-atomic resolution structure of the NuA4 co...

Recently, the Optical Society of America (Optica) announced the list of 2023 elected Fellows. A total of 109 scholars from 24 countries and regions around the world were selected. Professor Yu Jingyi of ShanghaiTech was elected for his contributions to computational imaging systems. Prof. Yu has long been engaged in the fields of computer vision, computational imaging, computer grap...

Staphylococcus aureus is a widespread Gram-positive pathogenic bacterium and is regarded as the main cause of skin and soft tissue infections. Due to the widespread use of antibiotics to kill bacteria, antibiotic-resistant bacteria have emerged. Functional metal nanoclusters can specifically detect S. aureus and exhibit antibacterial activity, which is favored as a “green” sterili...

The discovery of topological states and topological phase transitions has reshaped our understanding of physics and materials over the past few years. The topological transition from a normal insulator to a topological insulator (TI) can be realized by chemical or mechanical pressure. The topological transition was first predicted and demonstrated in Tl-based chalcogenides TlBi(S1−xSex)2 by i...

In November, Life Dean's Lecture of ShanghaiTech came again as scheduled. The Life Dean's Lecture is a special edition of the SLST Seminar held once a year, where distinguished experts in life sciences are invited to share the frontier scientific advances with faculty and students. This year, James Rothman, winner of the 2013 Nobel Prize in Physiology or Medicine and Distinguished Adjunct ...

Synthetic Lethality (SL) is a type of genetic interaction in which the simultaneous inactivation of two genes leads to cell death, while the inactivation of one gene alone does not affect the viability of the cell. In a pair of SL genes, if one gene has a cancer-specific mutation, the other gene can be a potential drug target because perturbation of the latter gene can selectively kill cancer cell...

As an important small molecule metabolite, NAD+ is widely involved in a series of biochemical reactions in cell energy metabolism, such as glycolysis, oxidative phosphorylation, and fatty acid oxidation. Tumor cells proliferate faster and are prone to DNA damage, requiring more NAD+ consumption. NAMPT is a key rate-limiting enzyme for NAD+ synthesis. Aberrant overexpression of NAMPT...

On October 28, ShanghaiTech won the gold medal in the 2022 International Genetically Engineered Machine Competition (iGEM) global finals among 350 teams from around the world. It is ShanghaiTech’s  sixth gold medal in this global student competition since its participation in 2016. The winning project is called “Mini Bioproduction Circle System on Mars Base (MBCS-Mars)”, conducte...