The first Symposium on Frontier in PROTAC Drug Discovery and Development was held on May 16th by the Shanghai Institute for Advanced Immunochemical Studies (SIAIS) at the Conference Center of ShanghaiTech University. This symposium received wide attention and enthusiastic response from the more than 600 attendees from enterprises and academia in China and abroad. Notably, more than half of the att...

On May 2nd, Advanced Science published a collaborative study from Drs. Liu Jia, Jiang Biao Laboratories of Shanghai Institute for Advanced Immunochemical Studies (SIAIS) and Dr. Jiang Xianxing from the School of Pharmaceutical Science at Sun Yat-Sen University, entitled “Photoactivatable Fluorogenic Labeling via Turn‐On “Click‐Like” Nitroso‐Diene Bioorthogonal Reaction”. Their study devel...

SLST Professor Shen Wei’s lab, in collaboration with Huazhong University of Science & Technology Professor Li Haohong’s Lab, have discovered a novel mechanism of predatory hunting and reward feeding. Their research, published on May 23rd in an article in Nature Neuroscience entitled “Zona incerta GABAergic neurons integrate prey-related sensory signals and induce an appetitive drive to...

A team of scientists led by SLST’s Dr. Zhang Hui and CAS Shanghai Institute of Biochemistry and Cell Biology’s Dr. Zhou Bin, has discovered a new mechanism for neonatal heart regeneration. Their findings suggest that cellular senescence that occurs after heart injury plays an essential role in neonatal heart regeneration. Their work, entitled “CCN1-Induced Cellular Senescence Promotes Heart Reg...

On May 26th, ShanghaiTech University signed a tripartite agreement with the Philadelphia Orchestra and the Shanghai Philharmonic Orchestra, formalizing a new strategic partnership that will strengthen communication across cultures and disciplines and boost the integration between science and arts.“At ShanghaiTech, we develop students’ academic potential in science and technology and nurture thei...

SPST scientists Professor Osamu Terasaki, Dr. Peter Oleynikov, Dr. Alvaro Mayoral and Dr. Ma Yanhang, have collaborated with Professor Kyung Byung Yoon to report a new layered vanadosilicate for removal of 90Sr from highly Na+-rich liquid nuclear waste. The paper was published in Energy & Environmental Science with the title of “Removal of 90Sr from highly Na+-rich liquid nuclear waste w...

A team of scientists led by SLST’s Dr. Qi Wei from and Dr. Song Baoliang from Wuhan University has identified Gpnmb as a liver-secreted factor promoting lipogenesis in white adipose tissue and aggravating obesity and insulin resistance. Using neutralizing antibody, they also demonstrated that reducing circulating Gpnmb brought therapeutic benefit to obesity and diabetes in animal models. This stu...

SEM Assistant Professor Zhou Xiaoyu, in collaboration with Peking University Associate Professor Zhang Yanlong and Singapore Management University Professor Wang Heli, studied empirically how Chinese firms translate their Corporate Social Responsibility (CSR) activities into financial market value through multiple paths. Their research was recently published in the Academy of Management Journal, e...

Recently, Assistant Professor Zhou Haotian at School of Entrepreneurship and Management published an empirical article titled “Conflating Temporal Advancement and Epistemic Advancement: The Progression Bias in Judgment and Decision Making” in Personality and Social Psychology Bulletin. Every decision-making process requires decision-makers to identify the values of choices and estimate its ...

Assistant Professor Yuu Kimata at School of Life Science and Technology published a review article titled ‘APC/C Ubiquitin Ligase: Coupling Cellular Differentiation to G1/G0 Phase in Multicellular Systems’ in Trends in Cell Biology in April 2019. The article reviews the recent progress on the molecular function of a protein complex, the Anaphase Promoting Complex/Cyclosome (APC/C), which is...

When the Intergovernmental Panel on Climate Change came out with their Special Report on Climate Change in October 2018, media attention focused on the short amount of time left to cut emissions before the 1.5-degree threshold that the signatory nations of the Paris Climate Change Agreement committed to is passed. At ShanghaiTech, School of Physical Science and Technology Professor Lin Bolin and t...

Recently, a research group led by iHuman Institute and SLST Assistant Professor Zhong Guisheng, working with collaborators SLST Assistant Professor He Shuijin and Southeast University Professor Chai Renjie, used a super-resolution fluorescence microscope to identify novel cytoskeleton ultrastructures in inner ear hair cell. Their two studies, “A cytoskeleton structure revealed by super-resolution...

Cancer is one of the biggest killers threatening human life and chemotherapy, which kills cancer cells with molecular drugs that are toxic to cells, is one of the main ways to treat cancer. For metastatic tumors, chemotherapy is the most effective method. However, chemotherapy drugs can also kill a large number of normal cells, causing severe toxic side effects and seriously damaging the physical ...

On April 12, Professor Matthew Freeman FRS, head of the Sir William Dunn School of Pathology at University of Oxford, visited ShanghaiTech.ShanghaiTech President Jiang Mianheng, together with SLST undergraduates, graduate students and postdocs welcomed the professor at a lunchtime gathering where they shared their ideas about potential collaborations. Before lunch, Vice President and Provost Yin J...