首页 > iHuman研究所 > 师资队伍 > 程建军个人简介
程建军    Research Associate Professor
所在学院 iHuman研究所
研究方向 药物化学
联系方式 chengjj@@shanghaitech.edu.cn
 
  个人简介  
2001.09 – 2005.06,山东大学药学院,药学学士;
2005.09 – 2010.07,中国科学院上海药物研究所,药物化学博士(导师:杨玉社);
2010.07 – 2013.10,上海汇伦生命科技有限公司,高级研究员、部门经理;
2013.11 – 2016.03,美国伊利诺伊大学芝加哥校区,博士后(导师:Alan P. Kozikowski);
2016.03至今,上海科技大学iHuman研究所,Research Associate Professor 、PI。
  主要研究内容  
基于GPCR靶点的药物设计、合成和开发。
  代表性论文  
1. Cheng, J.; Giguere, P. M.; Schmerberg, C. M.; Pogorelov, V. M.; Rodriguiz, R. M.; Huang, X.-P.; Zhu, H.; McCorvy, J. D.; Wetsel, W. C.; Roth, B. L.; Kozikowski, A. P.* Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists:  Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. J Med Chem, 2016, 59, 578–591.

2. Cheng, J.; Kozikowski, A. P.* We Need 2C but Not 2B: Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders. ChemMedChem ,2015, 10, 1963–1967.

3. Cheng, J.; Giguere, P. M.; Onajole, O. K.; Lv, W.; Gaisin, A.; Gunosewoyo, H.; Schmerberg, C. M.;  Pogorelov, V. M.; Rodriguiz, R. M.; Giulio Vistoli, G.;  Wetsel, W. C.; Roth, B. L.; Kozikowski, A. P.* Optimization of 2-Phenylcyclopropylmethylamines as Selective Serotonin 2C Receptor Agonists and Their Evaluation as Potential Antipsychotic Agents. J Med Chem, 2015, 58, 1992–2002.

4. Cheng, J.; Giguere, P. M.; Lv, W.; Roth, B. L.; Kozikowski, A. P.* Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)-methanamine as a Selective Serotonin 2C Agonist. Tetrahedron Lett, 2015, 56, 3420–3422.

5. Cheng, J.*; Qin, J.; Guo, S.; Qiu, H.; Zhong, Y. Design, Synthesis and Evaluation of Novel HDAC Inhibitors as Potential Antitumor Agents. Bioorg Med Chem Lett ,2014, 24, 4768–4772.

6. Cheng, J.; Liqiang Fu, L.; Chenyu Ling, C.; Yang, Y.* Total Synthesis of S-(–)-Stepholidine Using (S)-tert-Butanesulfinylimine. Heterocycles, 2010, 81, 2581–2592.

7. Cheng, J.-J.; Yang, Y.-S.* Enantioselective Total Synthesis of (–)-(S)-Stepholidine. J Org Chem, 2009, 74, 9225–9228.
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