Qiu Zilong Lectures on "Non-human Primate Model of Autism"
Author:School of Life Science and Technology            Date:2016-05-13            Browse:911

On May 12, Qiu Zilong, investigator of Institute of Neuroscience at the Chinese Academy of Sciences was invited to give a lecture on "non-human primate models of autism.”


Autism is a complex mental illness, and the development of animal models is critical for pathological research, drug development and translational research. Qiu’s group raised a transgenic monkey carrying the human autism gene MECP2 and did a molecular, genetic and behavioral analysis of these transgenic monkeys. They found that MECP2 transgenic monkeys showed repetitive locomotion, increased levels of anxiety, and stereotypical behavior social dysfunction, resembling human autistic patients. This work demonstrated that MECP2 overexpression in the brain directly leads to autism phenotype in non-human primates and produced a stable inherited non-human primate model of autism. This is the first non-human primate model of mental illness, which will provide an important animal model and research platform for further exploration of the neural mechanisms of autism and potential therapeutic interventions. 


Before the lecture, Professor Qiu had lunch with graduate students to talk about their lives as graduate students and their research trainings. After the lecture, Professor Qiu met with professors in Life Sciences about their academic experiences.